Our new, extremely sensitive, homogeneous luminescent
caspase-2 and -6 apoptosis assays provide unique tools for defining
the function of these elusive caspases. An understanding of
cross-reactivity between caspases, their substrates, and the
various peptide inhibitors is critical for interpreting results
from apoptosis studies. Here we provide details on using the Caspase-Glo® 2 Assay in cells.
Cell Notes 19, 8–13.
Martha O'Brien, Cassandra Broulette, Michael Scurria, Laurent Bernad and William Daily
Promega Corporation and Promega Biosciences