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P450Glo® CYP2C19 and CYP2D6 Assays and Screening Systems: The Method of Choice for in...

P450Glo® CYP2C19 and CYP2D6 Assays and Screening Systems: The Method of Choice for in vitro P450 Assays

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Abstract

The human cytochrome P450 enzymes CYP2C19 and CYP2D6 contribute substantially to the metabolism of therapeutic drugs. The P450-Glo® Assays for these enzymes enable researchers to assay activity and screen for P450 inhibition using a bioluminescent assay that minimizes background noise and is amenable to high-throughput applications.

Cell Notes 14, 20–24.

James J. Cali, Dongping MA, Mary Sobol, Troy Good and David Liu

Promega Corporation
Publication Date: 2006

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