HOXC5, homeobox C5

HOXC5, homeobox C5

• This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein Hox-C5, homeo box C5, homeobox protein CP11, homeobox protein Hox-3D, CP11, HOX3, HOX3D,)
• NCBI Gene ID: 3222
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q00444
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

homeobox C5 interacts with:

• golgi reassembly stacking protein 2
  LIM homeobox 3
  LIM homeobox 4
  PBX homeobox 1
  PBX homeobox 2
  PBX homeobox 4
  POU class 6 homeobox 2
  RNA polymerase II subunit G
  zinc finger and BTB domain containing 16

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.