CNOT2, CCR4-NOT transcription complex subunit 2

CNOT2, CCR4-NOT transcription complex subunit 2

• This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

• Gene Synonyms (CDC36, HSPC131, IDNADFS, NOT2, NOT2H, CCR4-NOT transcription complex subunit 2, CCR4-associated factor 2, negative regulator of transcription 2,)
• NCBI Gene ID: 4848
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KTL6
  UNIPROT ID#>>Q9NZN8
  UNIPROT ID#>>F8VV52
  UNIPROT ID#>>A0A024RBD8
  UNIPROT ID#>>B2RDX7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CCR4-NOT transcription complex subunit 2 interacts with:

• A-kinase interacting protein 1
  argonaute RISC catalytic component 2
  armadillo repeat containing 5
  aurora kinase A
  beta-transducin repeat containing E3 ubiquitin protein ligase
  brain expressed X-linked 1
  CCR4-NOT transcription complex subunit 1
  CCR4-NOT transcription complex subunit 10
  CCR4-NOT transcription complex subunit 11
  CCR4-NOT transcription complex subunit 3
  CCR4-NOT transcription complex subunit 4
  CCR4-NOT transcription complex subunit 6
  CCR4-NOT transcription complex subunit 6 like
  CCR4-NOT transcription complex subunit 7
  CCR4-NOT transcription complex subunit 8
  CCR4-NOT transcription complex subunit 9
  CCR4-NOT transcription complex, subunit 3
  chromosome 11 open reading frame 1
  chromosome 20 open reading frame 85
  CNKSR family member 3
  coiled-coil alpha-helical rod protein 1
  DEAD-box helicase 24
  DNA polymerase delta 1, catalytic subunit
  egl-9 family hypoxia inducible factor 3
  exportin 1
  GC-rich promoter binding protein 1 like 1
  germinal center associated signaling and motility
  heat shock transcription factor 2 binding protein
  histone deacetylase 3
  KAT8 regulatory NSL complex subunit 3
  La ribonucleoprotein 1, translational regulator
  ligand dependent nuclear receptor corepressor
  mitochondrial fission regulator 1 like
  mitochondrial ribosomal protein S12
  nanos C2HC-type zinc finger 2
  nemo like kinase
  nuclear receptor corepressor 1
  nuclear receptor corepressor 2
  ORC ubiquitin ligase 1
  polypeptide N-acetylgalactosaminyltransferase 10
  proline rich 35
  proteasome 20S subunit beta 4
  receptor for activated C kinase 1
  RIB43A domain with coiled-coils 1
  ribosomal protein L12
  ribosome binding protein 1
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  sequestosome 1
  SS18 like 2
  tankyrase 1 binding protein 1
  tankyrase 1 binding protein 1
  T-box transcription factor 2
  tektin 3
  testis expressed 13A
  transducer of ERBB2, 1
  transmembrane protein 165
  trinucleotide repeat containing adaptor 6A
  trinucleotide repeat containing adaptor 6B
  trinucleotide repeat containing adaptor 6C
  ubiquitin specific peptidase 24
  UPF1 RNA helicase and ATPase
  valosin containing protein
  WD repeat containing, antisense to TP73
  WD repeat domain 26
  zinc finger CCCH-type containing 7A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.