FLRT2, fibronectin leucine rich transmembrane protein 2

FLRT2, fibronectin leucine rich transmembrane protein 2

• This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

• Gene Synonyms (leucine-rich repeat transmembrane protein FLRT2, fibronectin-like domain-containing leucine-rich transmembrane protein 2,)
• NCBI Gene ID: 23768
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43155
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fibronectin leucine rich transmembrane protein 2 interacts with:

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