- Gene Overview
- Interaction Network
- Sequence Verification
VNN1, vanin 1
-
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009]
-
Gene Synonyms (pantetheinase, pantetheine hydrolase, vannin 1, vascular non-inflammatory molecule 1, HDLCQ8, Tiff66,)
- NCBI Gene ID:
8876
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>O95497
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
vanin 1 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|