Ease Your Transition to MPS
Massively parallel sequencing (MPS) offers a solution to the biggest challenges facing CE methods, such as distinguishing true allele variation from PCR artifacts, interpreting mixtures, and obtaining usable profiles from degraded DNA. However, adopting a new technology can have unique challenges. The PowerSeq® family of products can help make the transition a smooth one.
PowerSeq® 46GY System
Optimized panel of loci for STR analysis
The PowerSeq® 46GY System offers the same sensitivity as STR amplification kits. It can be used to prepare MPS libraries and generate sequencing data compatible with Illumina® sequencing technology. The kit enables identification of sequence variants in familiar autosomal and Y-STR loci, so that data generated are usable and interpretable with current guidelines.
PowerSeq® CRM Nested System, Custom
Streamlined library prep for mtDNA analysis
The PowerSeq® CRM Nested System, Custom, generates 10 small amplicons covering the control region of the mitochondrial genome in one multiplex reaction. This technique improves the results for degraded samples. The workflow greatly simplifies library preparation by saving time, decreasing sample loss and reducing data variability.
PowerSeq® Quant MS System
Consistent library prep for STR analysis
The PowerSeq® Quant MS System is a qPCR-based system designed for quantitation of libraries prior to sequencing on the Illumina® MiSeq® system. Accurate library quantitation provides balanced representation of pooled libraries and reduces sequencing bias.
Related Resources
Is MPS Right for Your Lab?
Things to consider if your lab is switching to an MPS workflow.
Harnessing the Power of MPS in Forensic Analysis
Validation study of the PowerSeq® CRM Nested System, Custom, presented at ISHI 29.
Webinar: Smoothing the Transition to MPS
Dr. Peter de Knijff discusses considerations around implementation of MPS in the forensic laboratory.