GTF2A1, general transcription factor IIA subunit 1

GTF2A1, general transcription factor IIA subunit 1

• Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]

• Gene Synonyms (transcription initiation factor IIA subunit 1, TFIIA alpha, p55, TFIIA alpha/beta subunits, general transcription factor IIA 1, general transcription factor IIA, 1, 19/37kDa, glucose regulated protein, 58kD pseudogene, transcription initiation factor TFIIA 42 kDa subunit, TF2A1, TFIIA, TFIIA-42, TFIIAL,)
• NCBI Gene ID: 2957
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P52655
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

general transcription factor IIA subunit 1 interacts with:

• agrin
  autophagy related 7
  baculoviral IAP repeat containing 7
  BOP1 ribosomal biogenesis factor
  CCR4-NOT transcription complex subunit 1
  CUE domain containing 2
  cytochrome b-245 chaperone 1
  dedicator of cytokinesis 7
  GCN1 activator of EIF2AK4
  general transcription factor IIA subunit 2
  general transcription factor IIE subunit 1
  general transcription factor IIE subunit 2
  general transcription factor IIF subunit 1
  golgi reassembly stacking protein 2
  heat shock protein family A (Hsp70) member 9
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  heterogeneous nuclear ribonucleoprotein A1
  high mobility group box 1
  inositol polyphosphate phosphatase like 1
  lamin A/C
  lysine demethylase 5B
  malic enzyme 1
  mohawk homeobox
  MYC proto-oncogene, bHLH transcription factor
  myosin light chain kinase 2
  niban apoptosis regulator 2
  nuclear receptor coactivator 6
  nuclear transcription factor Y subunit alpha
  pentatricopeptide repeat domain 2
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  proteasome 26S subunit, ATPase 6
  protein disulfide isomerase family A member 6
  prothymosin alpha
  radixin
  ring finger protein 4
  RNA pseudouridine synthase domain containing 2
  serine hydroxymethyltransferase 2
  seryl-tRNA synthetase 1
  sirtuin 1
  sorting nexin 6
  Sp4 transcription factor
  taspase 1
  TATA box binding protein
  TATA-box binding protein
  TATA-box binding protein associated factor 1
  TATA-box binding protein associated factor 4
  TATA-box binding protein associated factor 4b
  TATA-box binding protein associated factor 5
  TATA-box binding protein associated factor 6
  TATA-box binding protein like 1
  TATA-box binding protein like 2
  telomeric repeat binding factor 2
  thyroid hormone receptor interactor 4
  tubulin folding cofactor D
  UDP-glucose 6-dehydrogenase
  zinc finger E-box binding homeobox 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.