TNFRSF9, TNF receptor superfamily member 9

TNFRSF9, TNF receptor superfamily member 9

• The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

• Gene Synonyms (tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CD137 antigen, T cell antigen ILA, T-cell antigen 4-1BB homolog, homolog of mouse 4-1BB, induced by lymphocyte activation (ILA), interleukin-activated receptor, homolog of mouse Ly63, receptor protein 4-1BB, 4-1BB, CD137, CDw137, ILA,)
• NCBI Gene ID: 3604
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q07011
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF receptor superfamily member 9 interacts with:

• ceramide kinase
  leucine rich repeat protein 1
  solute carrier family 39 member 6
  sorting nexin 11
  stress associated endoplasmic reticulum protein 1
  TNF receptor associated factor 1
  TNF receptor associated factor 2
  TNF receptor associated factor 3
  TNF receptor associated factor 4
  TNF receptor associated factor 5
  TNF receptor superfamily member 4
  TNF receptor superfamily member 9
  TNF superfamily member 9

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