RASGRF2, Ras protein specific guanine nucleotide releasing factor 2

RASGRF2, Ras protein specific guanine nucleotide releasing factor 2

• RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]

• Gene Synonyms (ras-specific guanine nucleotide-releasing factor 2, ras guanine nucleotide exchange factor 2, GRF2, RAS-GRF2,)
• NCBI Gene ID: 5924
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14827
  UNIPROT ID#>>Q68DX5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Ras protein specific guanine nucleotide releasing factor 2 interacts with:

• epiplakin 1
  pantothenate kinase 2
  phosphomevalonate kinase
  Ras protein specific guanine nucleotide releasing factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.